Title:
乾燥粉末医薬製剤
Document Type and Number:
Japanese Patent JP2005507881
Kind Code:
A
Abstract:
A dry powder pharmaceutical composition comprising (i) a medicament particle fraction comprising medicament particles with an aerodynamic diameter no greater than 10 μm; and (ii) at least 50% of a non-respirable excipient fraction comprising low density excipient particles with an aerodynamic diameter greater than 10 μm and a geometric diameter greater than 30 μm. In additional embodiments of the invention, the pharmaceutical composition includes a respirable excipient fraction comprising excipient particles with an aerodynamic diameter no greater than 10 μm. In a preferred embodiment of the invention, the non-respirable excipient particles include pores adapted to receive a portion of the respirable excipient fraction and/or the medicament fraction.
Inventors:
Brown, Andrew, Bruce
Van haute, michael, mary
Van haute, michael, mary
Application Number:
JP2003528494A
Publication Date:
March 24, 2005
Filing Date:
September 16, 2002
Export Citation:
Assignee:
GLAXO GROUP LIMITED
International Classes:
A61K9/72; A61K9/00; A61K9/12; A61K9/14; A61K9/16; A61K9/26; A61K31/137; A61K31/56; A61K47/02; A61K47/10; A61K47/12; A61K47/18; A61K47/26; A61K47/34; A61K47/36; A61P11/08; A61P29/00; A61P37/08; (IPC1-7): A61K9/72; A61K9/14; A61K31/137; A61K31/56; A61K47/02; A61K47/10; A61K47/12; A61K47/18; A61K47/26; A61K47/34; A61K47/36; A61P11/08; A61P29/00; A61P37/08
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Ishii Teiji
Satoshi Fujita