Title:
二重光線療法用の染料-アジド化合物
Document Type and Number:
Japanese Patent JP2005503364
Kind Code:
A
Abstract:
The present invention discloses dye-azide derivatives and their bioconjugates for dual phototherapy of tumors and other lesions. The compounds of the present invention may contain either a mixture of Type 1 and Type 2 agents or a single entity that integrates both units in the same molecules. The compounds are designed to produce both Type 1 and Type 2 phototherapeutic effect at once using dual wavelength light source that will produce singlet oxygen and nitrene at the lesion of interest.
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Inventors:
Ragaban Rajago Paran
Samuel I Achirev
Joseph E. Bugaju
Richard B. Doshaw
Samuel I Achirev
Joseph E. Bugaju
Richard B. Doshaw
Application Number:
JP2003509836A
Publication Date:
February 03, 2005
Filing Date:
June 18, 2002
Export Citation:
Assignee:
Mallinckrodt INC.
International Classes:
C07D277/64; A61K31/409; A61K31/428; A61K41/00; A61K45/00; A61K47/48; A61P9/10; A61P35/00; A61P43/00; C07D487/22; C09B47/04; (IPC1-7): C07D277/64; A61K31/409; A61K31/428; A61K41/00; A61K45/00; A61K47/48; A61P9/10; A61P35/00; A61P43/00; C07D487/22
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima
Mitsutaka Iwasaki
Shoji Nakajima
Kazuaki Kojima
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