EGFR AND C-MET-FIBRONECTIN TYPE III DOMAIN BINDING MOLECULE

Title:

EGFR AND C-MET-FIBRONECTIN TYPE III DOMAIN BINDING MOLECULE

Document Type and Number:

Japanese Patent JP2022008534

Kind Code:

A

Abstract:

To provide further monospecific and bispecific EGFR and/or c-Met inhibitors for therapeutic and diagnostic applications.SOLUTION: Provided are monospecific and bispecific EGFR and/or c-Met FN3 domain containing molecules, isolated nucleotides encoding the molecules, vectors, host cells, and methods of making thereof. These monospecific and bispecific EGFR and/or c-Met FN3 domain containing molecules are useful for manufacturing therapeutic compositions for treatment and diagnosis of diseases and disorders such as cancer.SELECTED DRAWING: Figure 4

More Like This:

JP2024028379	Methods for selectively modulating the activity of different subtypes of cells
WO/2023/024759	FUSION PROTEIN OF INTERLEUKIN-2 AND APPLICATION THEREOF IN ALS
WO2000026394	VARIANTS OF HUMANIZED ANTI-CARCINOMA MONOCLONAL ANTIBODY CC49

Inventors:

MARK ANDERSON
RICARDO ATTAR
MICHAEL DIEM
LINUS HYUN
STEVEN JACOBS
ALASTAIR KING
DONNA KLEIN
SHERI MOORES
KARYN O'NEIL
KRISTEN PICHA

Application Number:

JP2021155530A

Publication Date:

January 13, 2022

Filing Date:

September 24, 2021

Export Citation:

Click for automatic bibliography generation Help

Assignee:

JANSSEN BIOTECH INC

International Classes:

C12N15/62; A61K39/395; A61P35/00; C07K14/765; C07K14/78; C07K16/00; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/12; C12N15/63; C12P21/02

Attorney, Agent or Firm:

Hiroshi Kobayashi
Junko Kobayashi
Norio Omori

Previous Patent: Compositions containing casein and methods for making them

Next Patent: Battery pack