Title:
エレヌマブ組成物及びその使用
Document Type and Number:
Japanese Patent JP2021519790
Kind Code:
A
Abstract:
本発明は、エレヌマブ並びに異性化バリアント、脱アミドバリアント、酸性バリアント、及びＨＭＷ種を含む１種以上のエレヌマブバリアントを含む組成物に関する。エレヌマブ組成物を含む医薬製剤並びに組成物を使用及び特徴付けする方法もまた記載される。
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Inventors:
Lawson, Kenneth
Leader, Noel
Hapuarachuchi, Sminda
Ramirez, Jose Gregorio
Leader, Noel
Hapuarachuchi, Sminda
Ramirez, Jose Gregorio
Application Number:
JP2020553476A
Publication Date:
August 12, 2021
Filing Date:
April 01, 2019
Export Citation:
Assignee:
Amgen Incorporated
International Classes:
C07K16/06; A61K39/395; A61P25/06; C07K16/28; C12P21/08
Domestic Patent References:
| JP2012509344A | 2012-04-19 | |||
| JP2015501836A | 2015-01-19 | |||
| JP2015502959A | 2015-01-29 |
Foreign References:
| WO2016171742A1 | 2016-10-27 | |||
| WO2016205037A1 | 2016-12-22 |
Other References:
WAGNER-ROUSSET E, ET AL.: "Development of a fast workflow to screen the charge variants of the rapeutic antibodies", J CHROMATOGR A, vol. 1498, JPN6023004771, 19 May 2017 (2017-05-19), pages 147 - 154, XP055607807, ISSN: 0004981419
YANG R, ET AL.: "High resolution separation of recombinant monoclonal antibodies by size-exclusion ultra-high perform", J PHARM BIOMED ANAL, vol. 109, JPN6023004772, 10 May 2015 (2015-05-10), pages 52 - 61, ISSN: 0004981420
YANG R, ET AL.: "High resolution separation of recombinant monoclonal antibodies by size-exclusion ultra-high perform", J PHARM BIOMED ANAL, vol. 109, JPN6023004772, 10 May 2015 (2015-05-10), pages 52 - 61, ISSN: 0004981420
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita