To provide an endoscope cleaning brush capable of reducing the cleaning time and enhancing the cleaning effect.

This endoscope cleaning brush is for cleaning the inside of a conduit formed inside an endoscope. The endoscope cleaning brush comprises a long body part 2 with flexibility to bend along the inner wall of the conduit when inserted into the conduit, a sponge part 3 mounted in the body part 2, and a brush part 4 mounted in the body part 2. The sponge part 3 is preferably made of a resin as a main material, and the resin is preferably a hydrophilic polymer.