Title:
免疫療法のためのエンゲージャー細胞
Document Type and Number:
Japanese Patent JP6420776
Kind Code:
B2
Abstract:
Embodiments concern methods and/or compositions related to immunotherapy for cancer. In particular embodiments, engager immune cells harbor a vector that encodes a secretable engager molecule. In particular cases, the engager molecule has an activation domain and an antigen recognition domain. In some embodiments, the engager molecules further comprise a cytokine or co-stimulatory domain, for example
Inventors:
Gottschalk, Stefan, M.G.
Song, Xiao-ton
Iwahori, coater
Velazquez, Mileya, Paulina
Abbott, Stewart
Song, Xiao-ton
Iwahori, coater
Velazquez, Mileya, Paulina
Abbott, Stewart
Application Number:
JP2015561624A
Publication Date:
November 07, 2018
Filing Date:
March 05, 2014
Export Citation:
Assignee:
BAYLOR COLLEGE OF MEDICINE
CELGENE CORPORATION
CELGENE CORPORATION
International Classes:
C12N5/0783; A61K35/12; A61K45/00; A61P35/00; C12N5/10; C12N15/13; C12N15/63; C12N15/86
Domestic Patent References:
| JP2015524255A | ||||
| JP2009521474A |
Foreign References:
| WO2012079000A1 | ||||
| WO2009091826A1 |
Other References:
Cancer Research,2007年,Vol. 67, No. 8,pp. 3927-3935
Attorney, Agent or Firm:
Patent Business Corporation Unias International Patent Office