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Title:
Enzymatic reductionism of alpha- and beta-dehydroamino acid using enoate Reductase
Document Type and Number:
Japanese Patent JP5992142
Kind Code:
B2
Abstract:
A method for the enzymatic preparation of amino acids of the general formula (3) or (4) from alpha-dehydroamino acids of the general formula (1) or (2) wherein R1, R2 are independently of one another H, C1-C6 alkyl, C2-C6 alkenyl, an optionally substituted carbo- or heterocyclic, aromatic or nonaromatic radical, or an alkylaryl radical, or a carboxyl radical (—COOR), R3 is H, formyl, acetyl, propionyl, benzyl, benzyloxycarbonyl, BOC, Alloc, R is H, C1-C6 alkyl, aryl, by reducing a compound of the formula (1) or (2) in the presence of a reductase.

Inventors:
Sturmer, liner
Bernhard, Hauer
Friedrich, Thomas
Favel, cart
Hall, melanie
Stacker, clemens
Application Number:
JP2010536486A
Publication Date:
September 14, 2016
Filing Date:
December 08, 2008
Export Citation:
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Assignee:
BASF SE
International Classes:
C12P13/04; C12N9/02; C12N15/09
Domestic Patent References:
JP2004520439A
JP2006174726A
Other References:
The Journal of Biological Chemistry,2003年,Vol.278,p.19891-19897
Angew.Chem.Int.Ed.,2007年,Vol.46,p.3934-3937
The Journal of Biological Chemistry,1995年,Vol.270,p.1983-1991
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Eiichi Arai
Natsuo Tanaka