Title:
液体処理、サーマルサイクリング及び精製を統合した迅速なDNA試料処理のための装置
Document Type and Number:
Japanese Patent JP2004500552
Kind Code:
A
Abstract:
The present invention provides, in one embodiment, a capillary cassette to facilitate rapid dialysis or thermocycling, via liquid or gas, of sub-microliter samples. In one embodiment, the invention is configured for use with a fluid handling machine for automated, high-throughput processing. Dialysis or thermocycling can be performed while the capillary cassette is mounted on the fluid handling machine. However, another embodiment of the invention provides higher throughput by the use of a hotel to simultaneously process a plurality of capillary cassettes. Hotel capabilities include dialysis, thermocycling, cleaning and chemical regeneration. Exemplary applications include but are not limited to polymerase chain reaction (PCR), DNA sequencing applications, oligonucleotide ligation, ligase chain reaction (LCR), single nucleotide extension, exonuclease treatment, and oligonucleotide hybridization assays.
Inventors:
Cahill patrick
Smith douglas
Soman ulrich
Angel stain mercy
Smith douglas
Soman ulrich
Angel stain mercy
Application Number:
JP2001524729A
Publication Date:
January 08, 2004
Filing Date:
September 21, 2000
Export Citation:
Assignee:
GENOME THERAPEUTICS CORPORATION
International Classes:
G01N35/10; B01D61/18; B01D61/28; B01D63/02; B01J19/00; B01L3/00; B01L3/02; B01L7/00; B01L99/00; C12M1/00; C12M1/12; C12M1/38; C12N15/09; C12Q1/68; C12Q1/6869; C12Q3/00; C40B60/14; G01N35/00; (IPC1-7): G01N35/10; B01L11/00; C12M1/00; C12M1/12; C12M1/38; C12N15/09; C12Q1/68; C12Q3/00
Attorney, Agent or Firm:
Tsutomu Kanakubo