Title:
薬理活性のある化合物の細胞内送達のためのカチオン脂質として有用な、L-カルニチンまたはアルカノイルL-カルニチンのエステル
Document Type and Number:
Japanese Patent JP5420507
Kind Code:
B2
Abstract:
Inventors:
Claudio Pisano
Maria Ornella Tinty
Moses Santaniello
Luciana Critelli
Giovanni Salvatori
Maria Ornella Tinty
Moses Santaniello
Luciana Critelli
Giovanni Salvatori
Application Number:
JP2010210849A
Publication Date:
February 19, 2014
Filing Date:
September 21, 2010
Export Citation:
Assignee:
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SOCIETA PER AZIONI
International Classes:
A61K31/437; A61K8/00; A61K8/11; A61K8/14; A61K8/30; A61K8/37; A61K8/44; A61K9/127; A61K31/225; A61K31/337; A61K31/4745; A61K39/00; A61K45/00; A61K47/18; A61K47/24; A61K47/28; A61K47/44; A61K48/00; A61P35/00; A61P37/04; A61Q19/00; C07C229/02; C07C229/22; C07C229/00
Foreign References:
| US5811406 | ||||
| WO1996040264A1 | ||||
| WO1996040265A1 | ||||
| EP0559625B1 | ||||
| WO1999057094A1 |
Other References:
DESHPANDE,D. et al,Target specific optimization of cationic lipid-based systems for pulmonary gene therapy,Pharm Res,1998年,Vol.15, No.9,p.1340-7
WANG,J. et al,Synthesis and characterization of long chain alkyl acyl carnitine esters. Potentially biodegradable cationic lipids for use in gene delivery,J Med Chem,1998年,Vol.41, No.13,p.2207-15
WANG,J. et al,Synthesis and characterization of long chain alkyl acyl carnitine esters. Potentially biodegradable cationic lipids for use in gene delivery,J Med Chem,1998年,Vol.41, No.13,p.2207-15
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Kenji Tomita
Mina Shiga
Hiroshi Yamazaki
Kenji Tomita
Mina Shiga