Title:
エストラトリエン誘導体
Document Type and Number:
Japanese Patent JP2006528207
Kind Code:
A
Abstract:
Compounds and methods for modulating mesenchymal cell function, for instance smooth muscle and fibroblast proliferation or cytokine expression, and for treating conditions associated with mesenchymal cell function, for instance airway hyperresponsiveness associated with asthma. The compounds also suppress inflammation. The compounds are a class of estratriene derivates, and includes various derivatives of 2-methoxyestradiol comprising a group A, including a substituted aromatic substituent in the 2-, 6- or 17-position.
Inventors:
George a la style stewart
James david micar listel
Nicholas Johon Lambert
James david micar listel
Nicholas Johon Lambert
Application Number:
JP2006529438A
Publication Date:
December 14, 2006
Filing Date:
May 13, 2004
Export Citation:
Assignee:
Crypto Pharma Pty Limited
International Classes:
C07J41/00; A61K31/565; A61K31/566; A61P11/00; A61P11/06; A61P11/08; A61P29/00; A61P43/00; C07J43/00
Foreign References:
| WO2001030803A1 | 2001-05-03 | |||
| WO2002032409A2 | 2002-04-25 | |||
| US6136992A | 2000-10-24 |
Attorney, Agent or Firm:
Toru Ishikawa