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Title:
潰瘍性大腸炎の検査方法および装置ならびに治療薬のスクリーニング方法
Document Type and Number:
Japanese Patent JP6906791
Kind Code:
B2
Abstract:
To provide an ulcerative colitis examination method and device, and therapeutic agent screening method useful for determining disease state of ulcerative colitis.SOLUTION: A ulcerative colitis examination method is disclosed. This method comprises: a step of performing an anaerobic culture using culture liquid including a fecal sample collected from a test subject; a step of collecting data of indicators of ulcerative colitis from the culture liquid; and a step of comparing the data with standard indicators from healthy individuals and/or individuals suffering from ulcerative colitis; wherein the anaerobic culture is performed with the culture liquid at a pH of 6.2 to 6.7 at the start of culturing and thereafter left standing. Furthermore, a therapeutic agent screening method for ulcerative colitis is disclosed. Additionally, an ulcerative colitis examination device is disclosed.SELECTED DRAWING: Figure 1

Inventors:
Kengo Sasaki
Namiko Hoshi
Jun Inoue
Token
Akira Osawa
Daisuke Sasaki
Akihiko Kondo
Application Number:
JP2017104859A
Publication Date:
July 21, 2021
Filing Date:
May 26, 2017
Export Citation:
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Assignee:
National University Corporation Kobe University
International Classes:
C12Q1/02; C12M1/34; C12Q1/18; G01N33/15; G01N33/50; G01N33/84
Foreign References:
WO2015136916A1
Other References:
日消外会誌,1983年,Vol. 16, No. 3,pp.552-556
Gut,2014年,Vol. 63,pp.1275-1283
Inflamm. Bowel Dis.,2016年,Vol. 22, No. 12,pp.2802-2810
mBio,2016年,Vol. 7, Issue 6,e01072-16
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takeshi Komatani
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto