Title:
EXPRESSION PROFILE IN ADULT AND FETAL ORGAN
Document Type and Number:
Japanese Patent JP2006246892
Kind Code:
A
Abstract:
To provide a method for screening medicines concerning to side effects harmful to cells, to provide a method for differentiating fetal and adult liver samples, to provide a method for differentiating fetal and adult cerebral tissues, and to provide a solid support for the methods.
Expression profiles have been constructed for liver and brain, in adult, fetal and adolescent tissue. These provide the probes which are highly differentially expressed among stages and organs. The profiles and probes can be used to prioritize potential drug targets, to monitor disease progression and remission, and to assess drug metabolism. Solid supports are also provided which facilitate these uses. By the above mentioned, the problems are settled.
Inventors:
LOCKHART DAVID J
NAIR ARCHANA
WARRINGTON JANET A
NAIR ARCHANA
WARRINGTON JANET A
Application Number:
JP2006103682A
Publication Date:
September 21, 2006
Filing Date:
April 04, 2006
Export Citation:
Assignee:
AFFYMETRIX INC
International Classes:
C12Q1/02; G01N33/50; C12M1/00; C12N15/09; C12Q1/68; C12Q1/6809; C12Q1/6837; C12Q1/6881; C12Q1/6883; G01N33/15; G01N33/53; G01N37/00
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita
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