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Title:
EXPRESSION VECTOR FOR BIOTRANSFORMATION OF MARCHANTIALES, BIOTRANSFORMATION PRODUCT OF MARCHANTIALES, AND METHOD FOR PRODUCING PROSTAGLANDIN BY THE BIOTRANSFORMATION PRODUCT
Document Type and Number:
Japanese Patent JP2013183639
Kind Code:
A
Abstract:

To provide an expression vector for biotransformation of a Marchantiales for making a high-expression of a cyclooxygenase involved in the biosynthesis of prostaglandins in the Marchantiales; to provide a biotransformation product of Marchantiales obtained by introducing the vector in the Marchantiales; and to provide a method for producing in vitro of a prostaglandin using extract of the biotransformation product of Marchantiales.

An expression vector for biotransformation of a Marchantiales includes: (A) DNA encoding a protein derived from an organism of Gracilariales having cyclooxygenase activity; and (B) DNA, situated upstream thereof, having 5'-UTR activity in Marchantiales biological cells.


Inventors:
OYAMA KANJI
KOBAYASHI MIHO
KANEMOTO KOSUKE
TOKUMOTO SHUICHI
OKIMURA YUKIO
TANAKA KOJIRO
YOSHIDA MASAAKI
Application Number:
JP2012048490A
Publication Date:
September 19, 2013
Filing Date:
March 05, 2012
Export Citation:
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Assignee:
ISHIKAWA PREFECTURAL PUBLIC UNIV CORP
International Classes:
C12N15/09; A01H11/00; A61K31/5575; A61P43/00; C12N5/10; C12P7/38; C07C51/47; C07C57/03
Attorney, Agent or Firm:
Ryu Iwatani