Title:
カンジダ・トロピカリスを阻害するソウカ精油の抽出方法及びソウカ精油
Document Type and Number:
Japanese Patent JP7447141
Kind Code:
B2
Abstract:
A method for extracting Tsaoko fructus essential oil for inhibiting candida tropicalis and the Tsaoko fructus essential oil. The extraction method comprises the following steps: weighing the ripe fruit of Tsaoko fructus, crushing and sieving same with a 30-50 mesh sieve to obtain a powder; mixing the powder with water, leaving the mixture to stand for 2-5 h, and then distilling the mixture with steam at 180°C-260°C for 5-8 h. Efficient extraction of the Tsaoko fructus essential oil is achieved by means of a steam distillation method, and the extraction rate reaches not less than 1.7%. The obtained Tsaoko fructus essential oil shows extremely strong inhibitory activity on candida tropicalis. The diameter of the bacteriostatic circle is not less than 15 mm, the MIC reaches not more than 0.195 μL/mL, and the MBC reaches not more than 0.781 μL/mL.
Inventors:
Yu Fukurai
胡 ▲シュアン▼
Wang Dan
▲陳▼ 悦
▲謝▼ 小▲麗▼
王 ▲凱▼
胡 ▲シュアン▼
Wang Dan
▲陳▼ 悦
▲謝▼ 小▲麗▼
王 ▲凱▼
Application Number:
JP2021560336A
Publication Date:
March 11, 2024
Filing Date:
July 16, 2021
Export Citation:
Assignee:
CHINA
International Classes:
A61K36/9064; A61P31/10; B01D11/02; C11B9/02
Foreign References:
| CN102716407A | ||||
| CN102716408A | ||||
| CN108096620A |
Other References:
Rapid Identification of Drug Resistant Candida Species Causing Recurrent Vulvovaginal Candidiasis,Med. Mycol. J,2012年,53,193-198,ISSN.2185-6486
Clinical characteristics of vulvovaginal candidiasis and antifungal susceptibilities of Candida species isolates among patients in southern China from 2003 to 2006,J. Obstet. Gynaecol. Res.,2008年,vol.34, no.4,pp.561-566,doi:10.1111/j.1447-0756.2008.00817.x
Chemical composition and antimicrobial activity of the essential oil of Amomum tsao-ko,J Sci Food Agric,2008年,88,pp.2111-2116,DOI: 10.1002/jsfa
Clinical characteristics of vulvovaginal candidiasis and antifungal susceptibilities of Candida species isolates among patients in southern China from 2003 to 2006,J. Obstet. Gynaecol. Res.,2008年,vol.34, no.4,pp.561-566,doi:10.1111/j.1447-0756.2008.00817.x
Chemical composition and antimicrobial activity of the essential oil of Amomum tsao-ko,J Sci Food Agric,2008年,88,pp.2111-2116,DOI: 10.1002/jsfa
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mihiro
Tatsuhiko Abe
Shinya Mihiro
Tatsuhiko Abe
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