To obtain the subject new hydrophilic preparation containing a salt or a monohydrate of 3-(1H-tetrazol-5-yl)oxanilic acid as an active ingredient, having excellent intraocular pressure lowing action and useful for glaucoma and ocular hypertension.
This eye drop contains a compound of the formula (X is an inorganic salt, an organic salt or a monohydrate) as an active ingredient. The monohydrate is preferably used as the active ingredient, because it is industrially advantageously obtained and readily soluble in water. As necessary, an isotonizing agent such as sodium chloride, a buffer such as boric acid, a stabilizer such as sodium edetate, a pH adjuster such as hydrochloric acid can be added to the preparation. The preparation is preferably formulated as an aqueous liquid preparation having about 3% concentration.
HOSHINA FUTOSHI
MATSUKAWA HIDEHIKO
TSURITANI MASATAKA
MAEDA MAKOTO