[F-18]-ラベルされたL-グルタミン酸、[F-18]-ラベルされたL-グルタミン、それらの誘導体、及びそれらの調製のためへのそれらの使用及び方法

Title:

[F-18]-ラベルされたL-グルタミン酸、[F-18]-ラベルされたL-グルタミン、それらの誘導体、及びそれらの調製のためへのそれらの使用及び方法

Document Type and Number:

Japanese Patent JP5529540

Kind Code:

B2

Abstract:

The compounds and the synthesis of [F-18]-labeled L-glutamic acid, [F-18]-labeled L-glutamate, their derivatives as set forth in formula (I) and their uses are described.

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Inventors:

Dinkelborg, Rutger
Fribe, matias
Krasikowa, Lysa Nikolaevna
Belocon, lily
Kuznetsova, Olga Fedorovna
Graham, Keith
Luhmann, Lutz
Matthias, Bernd
Schmidt-Billich, Helibelt

Application Number:

JP2009535027A

Publication Date:

June 25, 2014

Filing Date:

October 30, 2007

Export Citation:

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Assignee:

Piramal Imaging Society Anonymous
A.N.Mesyanov Institute of Organoelement Compounds The Russian Academy of Sciences
N.P. Bechute Leva Institute of the Human Brain of the Russian Academy of Sciences (IAB Bee)

International Classes:

C07C229/24; A61K51/00; C07B59/00; C07C227/12; C07C237/06; C07C269/06; C07C271/22

Domestic Patent References:

JP2006516547A

Foreign References:

WO2005101045A1
WO2005037737A1

Other References:

Laverman, Peter; Boerman, Otto C.; Corstens, Frans H. M.; Oyen, Wim J. G.,Fluorinated amino acids for tumour imaging with positron emission tomography,European Journal of Nuclear Medicine and Molecular Imaging ,2002年,29(5),681-690
Wu, Feng ET AL,Uptake of 14C- and 11C-labeled glutamate, glutamine and aspartate in vitro and in vivo,Anticancer Research,2000年,20(1A),251-256

Attorney, Agent or Firm:

Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe

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