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Title:
[F-18]-LABELED L-GLUTAMIC ACID, [F-18]-LABELED L-GLUTAMINE, DERIVATIVE THEREOF, AND USE AND METHOD THEREOF FOR PREPARATION THEREOF
Document Type and Number:
Japanese Patent JP2014088389
Kind Code:
A
Abstract:

To provide a diagnostic agent for positron emission tomography, comprising a [F-18]-labeled compound.

A diagnostic agent for positron emission tomography (PET) comprises a compound which is a L-glutamic acid or L-glutamic acid derivative labeled with F-18, represented by the formula (I). [In the formula, A represents hydroxyl, NH2 or O-Z; G represents hydroxyl or O-Z, R1 and R2 represent hydrogen or 18F, where any one of the substituents R1 or R2 is 18F isotope and the other substituent is hydrogen; and Z represents a metal cation.]


Inventors:
Ludger, Dinkelborg
Friebe, Matthias
Krasikowa, Raisa Nikolaevna
Yuri, Belokon
Kuznetsova, Olga Fedorovna
Keith, Graham
Lehmann, Lutz
Mathias, Berndt
Heribert, Schmitt-willich
Application Number:
JP2013000249418
Publication Date:
May 15, 2014
Filing Date:
December 02, 2013
Export Citation:
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Assignee:
PIRAMAL IMAGING SA
AN NESMEYANOV INSTITUTE OF ORGANOELEMENT COMPOUNDS THE RUSSIAN ACADAMY OF SCIENCES (INEOS RAS)
NP VETUTELLEVA INST OF THE HUMAN BRAIN OF THE RUSSIAN ACADEMY OF SCIENCES (IHB RAS)
International Classes:
A61K51/00; C07B57/00; C07B59/00; C07C229/24; C07C237/06; C07F15/04
Attorney, Agent or Firm:
青木 篤
石田 敬
福本 積
古賀 哲次
渡辺 陽一