Title:
A FGF receptor (FGFR) agonist dimeric compound, its manufacturing method, and its remedial use
Document Type and Number:
Japanese Patent JP6049756
Kind Code:
B2
Abstract:
The invention relates to novel heterocyclic compounds which are pyrazolopyridine derivatives that induce fibroblast growth factor receptor (FGFR) dimerization, having the general formula: M1-L-M2 in which M1 or M2, which may be identical or different, each represent, independently of one another, a monomer unit M and L represents a linker group which links M1 and M2 covalently with the monomer unit which follows: Process for the preparation thereof and therapeutic use thereof.
Inventors:
Marie-Line Clary-Secato
Natalie Gyo
Natalie Gyo
Application Number:
JP2014549609A
Publication Date:
December 21, 2016
Filing Date:
December 26, 2012
Export Citation:
Assignee:
SANOFI
International Classes:
C07D519/00; A61K31/437; A61P3/06; A61P9/00; A61P11/00; A61P17/02; A61P17/14; A61P19/02; A61P19/08; A61P21/00; A61P25/02; A61P27/02; A61P29/00; A61P37/06; A61P43/00
Domestic Patent References:
| JP2007519694A | ||||
| JP2003503481A | ||||
| JP2011500702A |
Foreign References:
| WO2007080325A1 | ||||
| WO2011023081A1 | ||||
| WO2011084486A1 | ||||
| US20070066641 |
Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Noriyuki Takebayashi
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