ＦＧＦＲキナーゼ阻害剤及び医薬用途

Japanese Patent JP7226804

B2

Fibroblast Growth Factor Receptor kinase inhibitors and prodrugs thereof of Formula (I) and their use for the treatment of hyper-proliferative diseases such as retinopathy, psoriasis, rheumatoid arthritis, osteoarthritis, septic arthritis, tumour metastasis, periodontal disease, corral ulceration, proteinuria, coronary thrombosis from atherosclerotic plaque, aneurismal aorta, dystrophobic epidermolysis bullosa, degenerative cartilage loss following traumatic joint injury, osteopenias mediated by MMP activity, tempero mandibular joint disease, and demyelating disease of the nervous system.

JP2009539936	Pyrazolopyrimidone
JP4920408	Compounds with nootropic action, methods for preparing them, pharmaceutical compositions having them, and their use.
WO/2020/000080	SYSTEM TO PREVENT AND TREAT THE BENDS AND BLOCKAGES OF BLOOD FLOWS

Paterson, Adam Vaughn
Smale, Jeffrey Bruce
Ashurzadeh, Amir
Guise, Christopher Paul
Squire, Christopher John
Gameji, Suvarnalata Akratiya
Abbatista, Maria Rosalia
Bull, Matthew Roy
Gray, Angus Cheverton
Li, Shwechian
din, ki
Ren, Xiaomei
Jian, Shuan
Tu, Zhenqiao

JP2019548023A

February 21, 2023

March 02, 2018

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AUCKLAND UNISERVICES LIMITED
Guanzhou Institute of Biomedicine and Health

C07D487/04; A61K31/4375; A61K31/519; A61K31/5377; A61P35/00; A61P35/02; A61P43/00; C07D471/04

JP2012520295A

WO2014182829A1
CN104418860A
WO2016192609A1

BUNDGAARD H,NOVEL CHEMICAL APPROACHES IN PRODRUG DESIGN,DRUGS OF THE FUTURE,ES,PROUS SCIENCE,1991年,Vol.16, No.5,p.443-458

Ikeda Adult
Junichiro Sakamaki
Masakazu Noda

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