Title:
ＦＧＦＲ４阻害剤及びその使用
Document Type and Number:
Japanese Patent JP7446287
Kind Code:
B2
Abstract:
Disclosed is a compound as a fibroblast growth factor receptor 4 (FGFR4) inhibitor (as shown in formula (I)), and a pharmaceutical composition thereof and a preparation method therefor, as well as the use of same in the treatment of FGFR4-mediated diseases. The above-mentioned compounds act by participating in a number of processes, such as regulating cell proliferation, apoptosis, migration, neovascularization.
Inventors:
Taka Kane Heng
grandchildren
Zhang Yi
Xu Xiaofeng
Liu Xiangyong
Royal family
Ding
grandchildren
Zhang Yi
Xu Xiaofeng
Liu Xiangyong
Royal family
Ding
Application Number:
JP2021517318A
Publication Date:
March 08, 2024
Filing Date:
September 26, 2019
Export Citation:
Assignee:
BETTA PHARMACEUTICALS CO.,LTD
International Classes:
C07D471/14; A61K31/519; A61K31/527; A61K31/5383; A61P35/00; A61P35/04; A61P43/00; C07D471/20; C07D487/14; C07D491/147; C07D495/14; C07D498/22; C07D513/14
Domestic Patent References:
| JP2015511245A | ||||
| JP2012514045A | ||||
| JP2017500335A |
Foreign References:
| WO2018004258A1 | ||||
| WO2018090939A1 | ||||
| WO2005021551A1 |
Other References:
REGISTRY(STN)[online],2008.06.10[検索日 2023.08.04] CAS登録番号 1027030-36-9
Attorney, Agent or Firm:
Patent Attorney Corporation Shuwa Patent Office
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