FUSED BICYCLIC mTOR INHIBITOR

Title:

FUSED BICYCLIC mTOR INHIBITOR

Document Type and Number:

Japanese Patent JP2010065049

Kind Code:

A

Abstract:

To provide a new compound presenting an mTOR inhibitory function in order to treat cancer patients.

A compound represented by formula (I) (wherein X1 is CH; each of X2, X3 and X5 is N; each of X4, X6 and X7 is C; Q1 is an optionally substituted indolyl group; and R3 is a cyclohexanecarboxylic acid group) or a pharmaceutically acceptable salt thereof is provided.

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Inventors:

CHEN XIN
COATE HEATHER
CREW ANDREW-PHILIP
DONG HAN-QING
HONDA AYAKO
MULVIHILL MARK JOSEPH
TAVARES PAULA A R
WANG JING
WERNER DOUGLAS S
MULVIHILL KRISTEN MICHELLE
SIU KAM W
PANICKER BIJOY
BHARADWAJ APOORBA
ARNOLD LEE D
JIN MEIZHONG
VOLK BRIAN
WENG QINGHUA
BEARD JAMES DAVID

Application Number:

JP2009255728A

Publication Date:

March 25, 2010

Filing Date:

November 09, 2009

Export Citation:

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Assignee:

OSI PHARM INC

International Classes:

C07D487/04; A61P35/00; A61P43/00; A61K31/53

Foreign References:

WO2005037836A2	2005-04-28
WO2005097800A1	2005-10-20
WO2005047289A1	2005-05-26

Attorney, Agent or Firm:

Yoshio Kawaguchi
Chihiro Watanabe
Katsuma Osaki
Mitsuaki Tsubokura

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