Title:
第ＸＩ因子抗体および使用方法
Document Type and Number:
Japanese Patent JP7139332
Kind Code:
B2
Abstract:
The present disclosure relates to monoclonal antibodies and antigen binding fragments thereof that bind to human Factor XI and activated Factor XI (“Factor XIa”), and pharmaceutical compositions and methods of treatment comprising the same.
Inventors:
Aigner, Maximilian
Koch, Alexander Wolfgang
Waldubert, Marx
Koch, Alexander Wolfgang
Waldubert, Marx
Application Number:
JP2019534393A
Publication Date:
September 20, 2022
Filing Date:
December 21, 2017
Export Citation:
Assignee:
Novartis Age
International Classes:
C07K16/36; A61K39/395; A61P7/02; A61P9/06; A61P9/10; C07K16/42; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/13; C12N15/63; C12P21/08
Domestic Patent References:
| JP2015517305A |
Foreign References:
| US20110159006 |
Other References:
Science Translational Medicine,2016年,Vol.8, No.353, 353ra112,pp.1-14
Thrombosis and Haemostasis,2013年,Vol.110,pp.1065-1073
Thrombosis and Haemostasis,2013年,Vol.110,pp.1065-1073
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Noriki Mihashi
Yasuhito Suzuki
Eiji Katayama
Norio Omori
Noriki Mihashi
Yasuhito Suzuki
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