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Patent Searching and Data


Title:
FARNESYLTRANSFERASE INHIBITOR FO-3929 AND ITS PRODUCTION
Document Type and Number:
Japanese Patent JPH07206886
Kind Code:
A
Abstract:

PURPOSE: To obtain a farnesyltransferase inhibitor being stable, low in toxicity and having strong enzyme inhibiting activity and to provide a method for producing the inhibitor.

CONSTITUTION: This method for producing FO-3929A substance, FO-3929B substance and/or FO-3929C substance comprises culturing a microorganism having ability producing FO-3929A substance, FO-3929B substance and/or FO-3929C substance which belongs to the genus Penicillium in a medium, accumulating E-3929A substance, FO-3929B substance and/or FO-3929C substance in the cultured mixture and collecting FO-3929A substance, FO-3929B substance and/or FO-3929C substance from the cultured mixture. In farnesyltransferase inhibitor, effect as an anticancer agent is expected.


Inventors:
OMURA SATOSHI
INOKOSHI JUNJI
MASUMA ROKUROU
IWAI YUZURU
Application Number:
JP1994000005194
Publication Date:
August 08, 1995
Filing Date:
January 21, 1994
Export Citation:
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Assignee:
KITASATO INST
International Classes:
C12N9/99; A61K45/00; A61P35/00; C07G99/00; (IPC1-7): C07G17/00; A61K45/00; C12N9/99
Attorney, Agent or Firm:
小林 和憲