Title:
Fast on-demand droplet generation and single cell encapsulation driven by induced cavitation
Document Type and Number:
Japanese Patent JP6367717
Kind Code:
B2
Abstract:
Methods and devices for the formation of droplets of a first fluid in a second fluid and the encapsulation of particles or cells within such droplets are disclosed. Impetus for droplet formation is provided by the creation of a transient bubble, which may be induced using a pulsed laser. Droplet volume and the frequency at which droplets are formed can be controlled by modulation of the pulsed laser. The disclosed methods and devices are particularly suitable for use in microfluidic devices.
Inventors:
Pay-You Chou
Tin-Cyan S. Wu
Sun-Young Park
Michael A. Tatel
Tin-Cyan S. Wu
Sun-Young Park
Michael A. Tatel
Application Number:
JP2014556753A
Publication Date:
August 01, 2018
Filing Date:
February 08, 2013
Export Citation:
Assignee:
The Regents of The University of California
International Classes:
B01J19/00; B81B1/00; B81B3/00; C12M1/00; C12M1/42; C12N11/14; C12Q1/02; G01N37/00
Domestic Patent References:
| JP2007515936A | ||||
| JP5240872A | ||||
| JP200465110A | ||||
| JP2001158099A | ||||
| JP2009100698A | ||||
| JP2003514236A |
Foreign References:
| US20110030808 | ||||
| WO2010092845A1 | ||||
| US20060128006 |
Other References:
Park, Sung-Yong,A PULSE LASER-DRIVEN MICROFLUIDIC DEVICE FOR ULTRA-FAST DROPLET GENERATION ON DEMAND AND SINGLE-CELLS ENCAPSULATION ,14th international Conference on Miniaturized Systems for Chemistry and Life Sciences, Groningen, The Netherlands, 2010, p.2129-2131
Park, Sung-Yong,High-speed droplet generation on demand driven by pulse laser-induced cavitation.,Lab on a chip,2011
Park, Sung-Yong,High-speed droplet generation on demand driven by pulse laser-induced cavitation.,Lab on a chip,2011
Attorney, Agent or Firm:
Yasuhiko Murayama
Shinya Mitsuhiro
Tatsuhiko Abe
Shinya Mitsuhiro
Tatsuhiko Abe