Title:
FDG SYNTHESIZER DESIGNED TO CARRY OUT DESOLVATION AND HYDROLYSIS SIMULTANEOUSLY ON CATION EXCHANGE RESIN COLUMN
Document Type and Number:
Japanese Patent JP3133251
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a FDG(fluorodeoxyglucose) synthesizer simplified in production porocess and capable of improving synthesis yield and shortening synthesis time.
SOLUTION: This FDG synthesizer is made up of a resin column for labeling reaction designed to trap F-18 anions contained on target water and then carry out a labeling reaction between the F-18 anions and triflate 12 and consisting of a column packed with an immobilized phase-transfer catalyst resin, and a cation exchange resin column 15 designed to heat an organic solvent-contg. intermediate formed by the labeling reaction to remove the organic solvent and bring the intermediate into contact with a H+ type-modified cation exchange resin to carry out a hydrolysis reaction of the intermediate and having a heating means and a flow rate control means for the organic solvent-contg. intermediate.
Inventors:
Shigeki Yamazaki
Katsuhiko Ohsaki
Katsuhiko Ohsaki
Application Number:
JP7553496A
Publication Date:
February 05, 2001
Filing Date:
March 29, 1996
Export Citation:
Assignee:
Nuke-Ke-Plant Construction Co., Ltd.
Nippon Steel Tube Co., Ltd.
Nippon Steel Tube Co., Ltd.
International Classes:
C07H5/02; A61K51/00; C07B59/00; (IPC1-7): C07H5/02
Domestic Patent References:
| JP55143999A | ||||
| JP7507813A |
Other References:
Ｎｕｃｌ．Ｍｅｄ．Ｂｉｏｌ．，Ｖｏｌ．１７，Ｎｏ．３（１９９０）ｐ．２７３−２７９
Attorney, Agent or Firm:
Yasuo Ishikawa (1 outside)