Title:
Feedback-tolerant alpha-isopropylmalic acid synthase
Document Type and Number:
Japanese Patent JP6341907
Kind Code:
B2
Abstract:
The invention relates to an isolated nucleotide sequence encoding an amino acid sequence that is at least ≧90%, ≧92%, ≧94%, ≧96%, ≧97%, ≧98%, ≧99% or 100%, preferably ≧97%, particularly preferably ≧98%, very particularly preferably ≧99%, and extremely preferably 0%, identical to the amino acid sequence of SEQ ID NO:2, wherein SEQ ID NO:2, at position 553, or at a corresponding position of the amino acid sequence, has a proteinogenic amino acid other than L-tyrosine, to a microorganism comprising the nucleotide sequence and also to a process for producing fine chemicals using this microorganism.
Inventors:
Roebeat Gestomair
Iris Vigreve
Iris Vigreve
Application Number:
JP2015507461A
Publication Date:
June 13, 2018
Filing Date:
April 12, 2013
Export Citation:
Assignee:
Evonik Technochemie GmbH
International Classes:
C12N15/09; C12N1/21; C12P7/40; C12P13/06
Domestic Patent References:
| JP2001037494A |
Other References:
Biochemistry,2009,48(31),p.7457-7464
Arch.Biochem.Biophys.,2012,519(2),p.202-209
Arch.Biochem.Biophys.,2012,519(2),p.202-209
Attorney, Agent or Firm:
Einzel Felix-Reinhard
Takuya Kuno
Takuya Kuno
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