Title:
フェンタニル含有経皮吸収製剤
Document Type and Number:
Japanese Patent JP5535640
Kind Code:
B2
Abstract:
It is intended to provide a novel fentanyl-containing percutaneous absorption preparation with reduced patient burden. The invention relates to the fentanyl-containing percutaneous absorption preparation to be administered once daily containing fentanyl or a salt thereof, particularly to the percutaneous absorption preparation wherein a standard deviation/average obtained from an average blood fentanyl concentration at daily intervals in consecutive 3 days after reaching a steady state by repeating administration thereof once daily is 40% or less.
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Inventors:
Higo adult
Tetsuishi Tetsuishi
Masaru Nakanishi
Takaaki Terahara
Hidehisa Minami
Shigeo Ohta
Nobuo Tsutsumi
Tetsuishi Tetsuishi
Masaru Nakanishi
Takaaki Terahara
Hidehisa Minami
Shigeo Ohta
Nobuo Tsutsumi
Application Number:
JP2009538162A
Publication Date:
July 02, 2014
Filing Date:
October 17, 2008
Export Citation:
Assignee:
Hisamitsu Pharmaceutical Co., Ltd.
International Classes:
A61K31/4468; A61K9/70; A61K47/12; A61K47/32; A61P25/04
Domestic Patent References:
| JPH1045570A | 1998-02-17 | |||
| JP2000044476A | 2000-02-15 | |||
| JP2004010552A | 2004-01-15 | |||
| JP2003137773A | 2003-05-14 | |||
| JPH03504977A | 1991-10-31 |
Foreign References:
| WO2004035054A1 | 2004-04-29 |
Other References:
JPN6008063307; 中山寛之他: 'デュロテップパッチ繰り返し適用時の血清中フェンタニル濃度挙動の予測' ＴＤＭ研究 Ｖｏｌ．２１ Ｎｏ．３, 2004, ｐ．２４８-２５４
JPN6008063310; ＤＯＮＮＥＲ，Ｂ． ｅｔ ａｌ: 'Ｌｏｎｇ-ｔｅｒｍ ｔｒｅａｔｍｅｎｔ ｏｆ ｃａｎｃｅｒ ｐａｉｎ ｗｉｔｈ ｔｒａｎｓｄｅｒｍａｌ ｆｅｎｔａｎｙｌ' Ｊ Ｐａｉｎ Ｓｙｍｐｔｏｍ Ｍａｎａｇｅ Ｖｏｌ．１５， Ｎｏ．３, 1998, ｐ．１６８-７５
JPN6008063313; ＫＯＲＴＥ，Ｗ． ｅｔ ａｌ: 'Ｄａｙ-ｔｏ-ｄａｙ ｔｉｔｒａｔｉｏｎ ｔｏ ｉｎｉｔｉａｔｅ ｔｒａｎｓｄｅｒｍａｌ ｆｅｎｔａｎｙｌ ｉｎ ｐａｔｉｅｎｔｓ ｗｉｔｈ ｃａｎｃｅｒ ｐａｉｎ： ｓｈｏｒｔ- ａｎｄ ｌｏｎｇ-' Ｊ Ｐａｉｎ Ｓｙｍｐｔｏｍ Ｍａｎａｇｅ Ｖｏｌ．１１， Ｎｏ．３, 1996, ｐ．１３９-４６
JPN7008008855; 久光製薬ニュースリリース , 20071015
JPN6008063308; 余宮きのみ: 'オピオイド鎮痛薬による痛みの治療の現況と展望' がん患者と対症療法 Ｖｏｌ．１４， Ｎｏ．２, 2003, ｐ．４７-５３
JPN6008063310; ＤＯＮＮＥＲ，Ｂ． ｅｔ ａｌ: 'Ｌｏｎｇ-ｔｅｒｍ ｔｒｅａｔｍｅｎｔ ｏｆ ｃａｎｃｅｒ ｐａｉｎ ｗｉｔｈ ｔｒａｎｓｄｅｒｍａｌ ｆｅｎｔａｎｙｌ' Ｊ Ｐａｉｎ Ｓｙｍｐｔｏｍ Ｍａｎａｇｅ Ｖｏｌ．１５， Ｎｏ．３, 1998, ｐ．１６８-７５
JPN6008063313; ＫＯＲＴＥ，Ｗ． ｅｔ ａｌ: 'Ｄａｙ-ｔｏ-ｄａｙ ｔｉｔｒａｔｉｏｎ ｔｏ ｉｎｉｔｉａｔｅ ｔｒａｎｓｄｅｒｍａｌ ｆｅｎｔａｎｙｌ ｉｎ ｐａｔｉｅｎｔｓ ｗｉｔｈ ｃａｎｃｅｒ ｐａｉｎ： ｓｈｏｒｔ- ａｎｄ ｌｏｎｇ-' Ｊ Ｐａｉｎ Ｓｙｍｐｔｏｍ Ｍａｎａｇｅ Ｖｏｌ．１１， Ｎｏ．３, 1996, ｐ．１３９-４６
JPN7008008855; 久光製薬ニュースリリース , 20071015
JPN6008063308; 余宮きのみ: 'オピオイド鎮痛薬による痛みの治療の現況と展望' がん患者と対症療法 Ｖｏｌ．１４， Ｎｏ．２, 2003, ｐ．４７-５３
Attorney, Agent or Firm:
Kiyoji Kuzuwa