Title:
上部胃腸管の安全性を高めるためのフィルムコーティング錠
Document Type and Number:
Japanese Patent JP5229641
Kind Code:
B2
Abstract:
A novel oral dosage to be delivered to the stomach comprising a safe and effective amount of an active ingredient selected from the group consisting of emepronium bromidebromide, doxycycline, and other tetracyclines/antibiotics, iron preparations, quinidine, nonsteroidal anti-inflammatory drugs, alprenolol, ascorbic acid, captopril, theophylline, zidovoudine (AZT), bisphosphonates and mixtures thereof and pharmaceutically-acceptable excipients, wherein said oral dosage form is a generally oval form and film coated to facilitate rapid esophageal transit and avoid irritation in the mouth, buccal cavity, pharynx, and esophagus.
Inventors:
Danselou, Richard, John.
Becker, Petras, Jacobs.
Becker, Petras, Jacobs.
Application Number:
JP2010127107A
Publication Date:
July 03, 2013
Filing Date:
June 02, 2010
Export Citation:
Assignee:
AJINOMOTO CO.,LTD.
International Classes:
A61K9/30; A61K9/20; A61K31/663; A61K9/28; A61K9/32; A61K9/34; A61K9/36; A61K9/40; A61K31/138; A61K31/375; A61K31/401; A61K31/49; A61K31/522; A61K31/65; A61K31/66; A61K31/675; A61K45/00; A61K47/32; A61K47/38; A61K47/42; A61P1/04
Other References:
DE GROEN, P.C. et al.,The New England Journal of Medicine,1996年,Vol.335, No.14,p.1016-1021
MARVOLA,M. et al.,Effect of dosage form and formulation factors on the adherence of drugs to the esophagus,J Pharm Sci,1983年,Vol.72, No.9,p.1034-1036
MARVOLA,M. et al.,Effect of dosage form and formulation factors on the adherence of drugs to the esophagus,J Pharm Sci,1983年,Vol.72, No.9,p.1034-1036
Attorney, Agent or Firm:
Yoshikazu Tani
Kazuo Abe
Kazuo Abe