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Title:
FILTER DEVICE FOR SELECTING AND REMOVING MONOCYTE AND/OR MACROPHAGE DERIVED FROM MONOCYTE
Document Type and Number:
Japanese Patent JP3812909
Kind Code:
B2
Abstract:

PROBLEM TO BE SOLVED: To obtain a filter device filled with a porous filter having a specific average pore cross section in a vessel having an inlet and an outlet and selectively removing monocyte and macrophage in a cell-floating solution, and useful for marrow transplantation and blood transfusion, etc.
SOLUTION: This filter device is useful for transplantation of a peripheral vascular cell, marrow transplantation, blood transfusion and removing of monocyte from blood of a patient having inflammatory disease, etc., with a very simple operation. Monocyte and/or macrophage derived from monocyte in a cell-floating solution can selectively be removed by winding a sheet of non-woven cloth, etc., made of polyethylene terephthalate, etc., having 10-20μm average fiber diameter in a hollow cylindrical shape having 1.8cm thickness of a filter part to obtain a porous filter having 100-500μm2 average pore cross section, filling the resultant filters in a hollow vessel having an inlet and an outlet of a liquid at both ends at a bulk density of 0.05-0.5g/cm3 and fixing the filters by providing a mesh-type supporter at the most inner peripheral part and the most outer peripheral part.


Inventors:
Hirokazu Onodera
Junsuke Suemitsu
Application Number:
JP25720195A
Publication Date:
August 23, 2006
Filing Date:
September 11, 1995
Export Citation:
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Assignee:
Asahi Kasei Medical Co., Ltd.
International Classes:
A61M1/02; G01N33/48; A61M1/34; A61M1/36; B01J20/22; C12N5/07; (IPC1-7): C12N5/06; A61M1/34; B01J20/22; //G01N33/48
Domestic Patent References:
JP7080062A
Attorney, Agent or Firm:
Toshitetsu Sasaki