FIXATION OF N-PROTECTING GROUP AMINO ACID ESTER

Title:

FIXATION OF N-PROTECTING GROUP AMINO ACID ESTER

Document Type and Number:

Japanese Patent JP2000044522

Kind Code:

A

Abstract:

To provide an industrial method for producing N-carbobenzoxy amino acid ester crystal.

Crystal of an N-protecting group amino acid ester is brought into contact with a melt of an N-protecting group amino acid ester, which is obtained by reacting an N-protecting group amino acid with alcohol in the presence of an acid catalyst, at ≤ the melting point. In this case, the content of solvent in the melt is ≤10%. The N-protecting group amino acid is N- carbobenzoxy-S-phenyl-L-cysteine.

Inventors:

OSABE MASAMI
KOITO MITSUO
YOSHINO SADAO
FUKUHARA NOBUHIRO

Application Number:

JP21435498A

Publication Date:

February 15, 2000

Filing Date:

July 29, 1998

Export Citation:

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Assignee:

MITSUI CHEMICALS INC

International Classes:

C07C227/42; C07C229/00; C07C319/20; C07C323/58; (IPC1-7): C07C229/00; C07C227/42; C07C319/20; C07C323/58

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