Title:
組織を修復するための固定具
Document Type and Number:
Japanese Patent JP5345043
Kind Code:
B2
Abstract:
Fixation devices for tissue repair, for example sutures, surgical arrows, staples, darts, bolts, screws, buttons, anchors, nails, rivets or barbed devices comprise at least one of angiogenic material; angiogenic precursor material which is capable of breaking down in vivo to form angiogenic material; and tissue-engineered material, which tissue-engineered material is capable of producing angiogenic material. In a preferred form the material is incorporated into a polymer matrix having predetermined hydrophobicity to allow controlled release of angiogenic materials such as butyric or hydroxybutyric acid or salts thereof. Polymer matrix compositions comprising angiogenic materials and methods for tissue repair are also provided.
Inventors:
Emma Jane Wright
James William Hackle
Third A Bowl Majede Ali
James William Hackle
Third A Bowl Majede Ali
Application Number:
JP2009266561A
Publication Date:
November 20, 2013
Filing Date:
November 24, 2009
Export Citation:
Assignee:
SMITH & NEPHEW PUBLIC LIMITED COMPANY
International Classes:
A61B17/56; A61L17/00; A61F2/06; A61F2/08; A61F2/28; A61L27/00; A61L31/04; A61L31/14; A61L31/16; A61L33/00
Domestic Patent References:
| JP64086974A | ||||
| JP2000512519A | ||||
| JP10305105A |
Foreign References:
| WO1998058690A1 | ||||
| WO1990011071A1 |
Other References:
Dobson DE et al.,1-Butyryl-glycerol: a novel angiogenesis factor secreted by differentiating adipocytes.,Cell. ,1990年 4月20日,61(2),223-30
Yonekura K et al.,UFT and its metabolites inhibit the angiogenesis induced by murine renal cell carcinoma, as determined by a dorsal air sac assay in mice.,Clin Cancer Res,1999年 8月,5(8),2185-91
Yonekura K et al.,UFT and its metabolites inhibit the angiogenesis induced by murine renal cell carcinoma, as determined by a dorsal air sac assay in mice.,Clin Cancer Res,1999年 8月,5(8),2185-91
Attorney, Agent or Firm:
Yasuhiko Murayama
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro
Masatake Shiga
Takashi Watanabe
Shinya Mitsuhiro