Title:
FLAVAN DERIVATIVE, SKIN FIBROBLAST PROLIFERATION INHIBITOR AND EXTERNAL PREPARATION FOR SKIN
Document Type and Number:
Japanese Patent JP2003267966
Kind Code:
A
Abstract:
To provide a means for inhibiting the formation of hypertrophic scar caused on the restoration of the skin.
A compound having a structure represented by the general formula (I) (R1, R2, R3, R4 or R5 are each independently a 1 to 4C alkyl; R is H, a 1 to 4C acyl or a sugar residue) or its salt. An external preparation for the skin contains the compound or its salt.
Inventors:
KAWAI MITSUO
TADA AKIHIRO
KATAGIRI TAKAYUKI
TADA AKIHIRO
KATAGIRI TAKAYUKI
Application Number:
JP2002068301A
Publication Date:
September 25, 2003
Filing Date:
March 13, 2002
Export Citation:
Assignee:
POLA CHEM IND INC
International Classes:
A61K8/00; A61K8/49; A61K31/353; A61P17/00; A61Q19/00; C07D311/60; (IPC1-7): C07D311/60; A61K7/00; A61K7/48; A61K31/353; A61P17/00
Domestic Patent References:
| JP2002501914A | 2002-01-22 | |||
| JPH11508549A | 1999-07-27 | |||
| JP2000516219A | 2000-12-05 | |||
| JP2001520202A | 2001-10-30 | |||
| JP2001288083A | 2001-10-16 |
Foreign References:
| WO2000071135A1 | 2000-11-30 | |||
| US20010025034A1 | 2001-09-27 | |||
| WO1999030707A1 | 1999-06-24 |
Other References:
山本恵申: "スギナ(Equisetum arvense LINN'E)抽出粗タンパク質による培養(ガン)細胞増殖抑制効果", 生物試料分析, vol. 22, no. 5, JPN6008047426, 1999, pages 421 - 424, ISSN: 0001136733
Attorney, Agent or Firm:
Tsutomu Toyama (2 outside)