Title:
FLOW THROUGH PURIFICATION PROCESS FOR LARGE BIOMOLECULE
Document Type and Number:
Japanese Patent JP2011128147
Kind Code:
A
Abstract:
To provide novel and improved flow-through purification processes, at least in part, for separating large biomolecules, such as, for example, encapsulated viruses, virus-like particles or conjugate vaccines, from one or more contaminants in a sample.
The process employs the use of at least one population of a solid porous particle which comprises a minimized external surface area per unit volume of the particles and an internal surface area per unit volume which is not decreased by more than 25% relative to a population of a similar particle which does not have a minimized external surface area.
Inventors:
IYER GANSPATHYSUBRAMANIAN (US)
RAMASWARMY SENTHIL (US)
CHENG KWOK-SHUN (US)
RAMASWARMY SENTHIL (US)
CHENG KWOK-SHUN (US)
Application Number:
JP2010263504A
Publication Date:
June 30, 2011
Filing Date:
November 26, 2010
Export Citation:
Assignee:
MILLIPORE CORP
International Classes:
G01N30/88; B01D15/04; B01D15/08; C12N1/02; C12N7/02
Attorney, Agent or Firm:
Kawaguchi International Patent Office
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