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Title:
FLUORESCENT LABELED STEROID COMPOUND AND METHOD FOR PRODUCING THE SAME
Document Type and Number:
Japanese Patent JP2004277312
Kind Code:
A
Abstract:

To provide a new ligand which enables the simple and rapid detection of a target base sequence in a homogeneous system not needing a B/F separation treatment in an aptamer method for detecting a target base sequence with the bonding affinity of a nucleic acid aptamer with the ligand as an indicator.

This fluorescent labeled steroid compound is characterized by binding a fluorescent molecule to a steroid skeleton-having compound. The fluorescent labeled steroid compound is, for example, represented by the formula [R1 and R2 are each independently H, OH, a 1 to 5C straight chain or branched alkyl, amino, phenyl or benzyl; R5, R6 and R7 are each independently H or OH; (n) is an integer of 1 or 10].


Inventors:
Miyamoto, Nobuaki
Takemura, Taro
Kato, Teru
Suzuki, Hideyuki
Application Number:
JP2003000069145
Publication Date:
October 07, 2004
Filing Date:
March 14, 2003
Export Citation:
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Assignee:
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL & TECHNOLOGY
International Classes:
G01N21/64; C07J17/00; C09K11/06; C12Q1/68; G01N21/78; G01N33/53; G01N33/566; G01N33/58; (IPC1-7): C07J17/00; C09K11/06; C12Q1/68; G01N21/64; G01N21/78; G01N33/53; G01N33/566; G01N33/58



 
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