Title:
少なくとも1のオリゴヌクレオチドに共有結合するフルオロフォアを含みかつ少なくとも1の官能基を含む蛍光物質、並びにその使用
Document Type and Number:
Japanese Patent JP2005529219
Kind Code:
A
Abstract:
A fluorescent entity (U) comprises: a fluorophore (except a rare earth metal cryptate); and at least one functional group, introduced or generated on the fluorophore or one of oligonucleotides or oligonucleotide analogs. The fluorophore is covalently attached to at least one oligonucleotide(s) or oligonucleotide analog(s). Independent claims are also included for: (1) A fluorescent conjugate consisting of the entity covalently attached to a carrier molecule; and (2) A method for increasing the fluorescence intensity of a fluorophore, for decreasing the aggregation at the surface or for increasing quantum yield of a fluorophore attached to a carrier molecule, in which a fluorescent entity is used as a fluorophore.
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Inventors:
Tranque, eric
Moran, Fabrice
Elbe, Bazan
Matisse, Gerard
Moran, Fabrice
Elbe, Bazan
Matisse, Gerard
Application Number:
JP2004511721A
Publication Date:
September 29, 2005
Filing Date:
June 06, 2003
Export Citation:
Assignee:
Sibio International
International Classes:
C07H21/00; C09B11/28; C09B23/00; C09B57/00; C09B69/10; C12Q1/00; G01N21/78; G01N33/533; (IPC1-7): C09B69/10; C09B11/28; C09B23/00; C09B57/00; C12Q1/00; G01N21/78
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Masaya Nishiyama