Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
FLUORINATED GANGLIOSIDE GM3
Document Type and Number:
Japanese Patent JPH07126278
Kind Code:
A
Abstract:

PURPOSE: To obtain a new compound having a new cell proliferation suppressing mechanism, promising as a carcinostatic agent, a carcinostatic and metastasis suppressing agent, etc., and capable of readily synthesizing.

CONSTITUTION: A compound is expressed by formula I [(m) is ≥2; (n) is 0-7, with the proviso that (m)>(n); R is an alkyl or a fluoroalkyl] e.g. O-(5- acetamide-3,5-dideoxy-D-glycero-α-D-galacto-2-nonyuropyranosylonic acid)-(2→3)- O-(β-D-galactopyranosyl)-(1→4)-O-(β-D-glucopyranosyl) (1→1)-(2S,3R,4E)-10- perfluorooctyl-2-tetracosanamide-4-decene-1,3-diol. This compound is obtained by reacting, e.g. a compound of formula II with (2S,3R,4E)-2-azide-3- benzoyloxy-10-perfluorooctyl-4-decene-1-ol and then, successively reacting the resultant compound with hydrogen sulfide and tetracosanoic acid and then reacting the product with sodium methoxide and water.


Inventors:
IIDA TAKAO
OHIRA YUTAKA
Application Number:
JP33166193A
Publication Date:
May 16, 1995
Filing Date:
December 27, 1993
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
DAIKIN IND LTD
International Classes:
A61K31/715; A61P35/00; C07C47/24; C07C247/08; C07H15/10; C07H15/18; (IPC1-7): C07H15/10; C07C47/24; C07C247/08
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)