Title:
FORMULATED LIQUID PREPARATION OF VITAMIN B1
Document Type and Number:
Japanese Patent JPH11322609
Kind Code:
A
Abstract:
To obtain a liquid preparation for internal use in which stability of vitamin B1s is nearly equivalent to a liquid preparation using sucrose as a saccharide by formulating an isomerized sugar from which ninhydrin reaction substance is removed with vitamin B1s.
This liquid preparation is obtained by formulating an isomerized sugar from which ninhydrin reaction substance is substantially removed preferably by purification by an ion exchange resin, activated carbon, etc., with vitamin B1s such as thiamine or sulthiamine and preferably further formulating at least one kind of organic acids and inorganic acids therewith. Furthermore, the formulating amount of the isomerized sugar is preferably 5-48 W/V% based on total liquid preparation.
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Inventors:
SASAKI YUICHI
NAKAJIMA TOSHIAKI
TAMAYA TAKATSUGU
TSUCHIDA SACHIKO
KAMATA SUNAO
HIROHASHI TOSHIO
MIYASHITA YUJI
NAKAJIMA TOSHIAKI
TAMAYA TAKATSUGU
TSUCHIDA SACHIKO
KAMATA SUNAO
HIROHASHI TOSHIO
MIYASHITA YUJI
Application Number:
JP13217698A
Publication Date:
November 24, 1999
Filing Date:
May 14, 1998
Export Citation:
Assignee:
TAISHO PHARMACEUTICAL CO LTD
GUNEI KAGAKU KOGYO KK
GUNEI KAGAKU KOGYO KK
International Classes:
A61K31/51; A61K31/70; A61P3/02; A61K9/08; (IPC1-7): A61K31/51; A61K9/08; A61K31/70
Domestic Patent References:
| JPH10120559A | 1998-05-12 | |||
| JPH1067660A | 1998-03-10 | |||
| JPH07112933A | 1995-05-02 | |||
| JPH0959150A | 1997-03-04 |
Other References:
高純度化技術大系第３巻 高純度物質製造プロセス, JPN7008009105, 1997, pages 340 - 347, ISSN: 0001213627
Attorney, Agent or Firm:
Kitagawa Fuzo