Title:
ニューロキニンアンタゴニストを含む製剤
Document Type and Number:
Japanese Patent JP2010513356
Kind Code:
A
Abstract:
Pharmaceutical compositions in the form of a solid dispersion comprising (4R)-4-[N'-methyl-N'-(3,5-bistrifluoromethyl-benzoyl)-amino]-4-(3,4-dichlorobenzyl)-but-2-enoic acid N-[(R)-cpsilon-caprolactam-3-yl]-amidc or a pharmaceutically acceptable salt or solvate thereof and a carrier. Such compositions are useful to treat patients who have functional motility disorders of the viscera, especially irritable bowel syndrome or functional dyspepsia, or urinary bladder disorders, especially urinary incontinence.
Inventors:
Anke Diederich
Carsten Timpe
Angelica Reese
Isabelle Ottinger
Irene Mueller
Michael Herbig
Helmut Schutz
Jay Pershban Lakshman
Oscar Culp
Carsten Timpe
Angelica Reese
Isabelle Ottinger
Irene Mueller
Michael Herbig
Helmut Schutz
Jay Pershban Lakshman
Oscar Culp
Application Number:
JP2009541897A
Publication Date:
April 30, 2010
Filing Date:
December 20, 2007
Export Citation:
Assignee:
Novartis Age
International Classes:
A61K31/55; A61K9/10; A61K9/14; A61K9/20; A61K47/04; A61K47/12; A61K47/26; A61K47/32; A61K47/36; A61K47/38; A61P1/04; A61P1/12; A61P1/14; A61P11/00; A61P11/06; A61P13/02; A61P13/10
Domestic Patent References:
JP2008536913A | 2008-09-11 | |||
JP2001521899A | 2001-11-13 | |||
JP2007509184A | 2007-04-12 | |||
JP2007520521A | 2007-07-26 | |||
JP2001503387A | 2001-03-13 | |||
JP2003526666A | 2003-09-09 | |||
JPH054919A | 1993-01-14 | |||
JP2004131393A | 2004-04-30 |
Foreign References:
WO2005039563A2 | 2005-05-06 | |||
WO2005074891A1 | 2005-08-18 | |||
WO2006112649A1 | 2006-10-26 |
Attorney, Agent or Firm:
Mitsuo Tanaka
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Masayuki Nakagawa
Takuji Yamada
Mitsutaka Iwasaki
Aoyama Aoi
Masayuki Nakagawa