Title:
自由溶液リガンド相互作用分子分離方法
Document Type and Number:
Japanese Patent JP4303885
Kind Code:
B2
Abstract:
The present invention is directed to novel methods for enhancing the ability to separate a species of interest from other different species present in a free solution mixture thereof which takes advantage of interactions that occur between soluable, small molecular weight ligands and the species of interest. The small molecular weight ligands employed in the present invention function to interact with a species of interest in a mixture of different species through either affinity, hydrophobic and/or ionic interactions, thereby altering the molecular weight, hydrodynamic volume and/or isoelectric point of the species of interest and rendering it separable from other component(s) in the mixture.
Inventors:
Van rice, robert, dee
Application Number:
JP2000526537A
Publication Date:
July 29, 2009
Filing Date:
December 10, 1998
Export Citation:
Assignee:
GENENTECH,INC.
International Classes:
B01D15/08; C12N15/09; B01D11/04; B01D15/02; B01D61/02; B01D61/14; C07K1/16; C07K1/20; C07K1/22; C07K1/32; C12N7/02; G01N30/02; G01N30/06; G01N30/88
Domestic Patent References:
| JP59044322A |
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori