Title:
機能性組成物
Document Type and Number:
Japanese Patent JP7095861
Kind Code:
B2
Abstract:
To provide a technique which simultaneously reacts a component derived from Angelica keiskei with a component derived from Olea europaea L. and thereby synergistically exerts their functionality.SOLUTION: Provided is a functional composition, an oxidative stress-preventing or improving composition, a vascular endothelium-protecting or wound healing-promoting composition, an active oxygen-eliminating or detoxifying composition, or an endothelial nitric oxide synthase-activating composition, which simultaneously or separately comprises (1) xanthoangelol and/or 4-hydroxyderricin and (2) hydroxytyrosol and/or oleuropein as active ingredients. The composition is preferably in the form of food, medicine, quasi drug, cosmetic, supplement, veterinary drug or feed.SELECTED DRAWING: None
Inventors:
Miyazaki Hitoshi
Daichi Kokufu
Shan Ray
Daichi Kokufu
Shan Ray
Application Number:
JP2018043474A
Publication Date:
July 05, 2022
Filing Date:
March 09, 2018
Export Citation:
Assignee:
National University Corporation University of Tsukuba
International Classes:
A61K31/7048; A23K20/111; A23K20/121; A23L33/10; A23L33/105; A61K8/34; A61K8/35; A61K8/60; A61K8/9789; A61K31/05; A61K31/12; A61K36/232; A61K36/63; A61P9/14; A61P17/02; A61P39/06; A61P43/00; A61Q19/00
Domestic Patent References:
| JP2007186515A | ||||
| JP2016033131A | ||||
| JP2012102055A | ||||
| JP2009191012A | ||||
| JP2011037811A | ||||
| JP2003146870A | ||||
| JP2004210759A | ||||
| JP2009107965A | ||||
| JP7223940A |
Foreign References:
| WO2004014407A1 |
Other References:
宮崎 均,多様な有効活用が可能なオリーブ成分,生物工学,2013年,91巻3号,159
Takumaru Hisatome,Promotion of Endothelial Wound Healing by the Chalcones 4-hydroxyderricin and Xanthoangelol, and the Molecular Mechanism of This Effect,Journal of Developments in Sustainable Agriculture,2017年,12巻1号,25-33
Romero M,Antihypertensive effects of oleuropein-enriched olive leaf extract in spontaneously hypertensive rats,Food Funct,2016年,7巻1号,584-593
Peyrol, Julien,Hydroxytyrosol in the Prevention of the Metabolic Syndrome and Related Disorders,Nutrients,2017年,9巻3号,Article No 306
Zrelli H,Hydroxytyrosol induces proliferation and cytoprotection against oxidative injury in vascular endothelial cells: role of Nrf2 activation and HO-1 induction,J Agric Food Chem,2011年,59巻9号,4473-4482
Takumaru Hisatome,Promotion of Endothelial Wound Healing by the Chalcones 4-hydroxyderricin and Xanthoangelol, and the Molecular Mechanism of This Effect,Journal of Developments in Sustainable Agriculture,2017年,12巻1号,25-33
Romero M,Antihypertensive effects of oleuropein-enriched olive leaf extract in spontaneously hypertensive rats,Food Funct,2016年,7巻1号,584-593
Peyrol, Julien,Hydroxytyrosol in the Prevention of the Metabolic Syndrome and Related Disorders,Nutrients,2017年,9巻3号,Article No 306
Zrelli H,Hydroxytyrosol induces proliferation and cytoprotection against oxidative injury in vascular endothelial cells: role of Nrf2 activation and HO-1 induction,J Agric Food Chem,2011年,59巻9号,4473-4482
Attorney, Agent or Firm:
Creation International Patent Office
Shigeru Matsui
Taketaka Miyao
Shigeru Matsui
Taketaka Miyao