Title:
FUNCTIONALIZED NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME
Document Type and Number:
Japanese Patent JP2023123714
Kind Code:
A
Abstract:
To provide methods of forming functionalized nanoparticles.SOLUTION: Described is a versatile surface modification approach to, for example, modularly and orthogonally functionalize nanoparticles (NPs) such as PEGylated nanoparticles, with various types of different functional ligands (functional groups) on the NP surfaces. It enables the synthesis of, for example, penta-functional PEGylated nanoparticles integrating a variety of properties into a single NP, e.g., fluorescence detection, specific cell targeting, radioisotope chelating/labeling, ratiometric pH sensing, and drug delivery, while the overall NP size remains, for example, below 10 nm.SELECTED DRAWING: None
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Inventors:
MA KAI
ULRICH B WIESNER
ULRICH B WIESNER
Application Number:
JP2023105610A
Publication Date:
September 05, 2023
Filing Date:
June 28, 2023
Export Citation:
Assignee:
UNIV CORNELL
International Classes:
A61K9/00; A61K47/69; A61K49/18; B82Y5/00; B82Y40/00
Attorney, Agent or Firm:
Patent Attorney Corporation Minori Patent Office