Title:
ＭＮＫ阻害剤としての縮合チアゾロピリミジン誘導体
Document Type and Number:
Japanese Patent JP7181647
Kind Code:
B2
Abstract:
The present invention relates to compounds of formulae I and II, or pharmaceutically acceptable salts or esters thereof.Further aspects of the invention relate to pharmaceutical compositions and therapeutic uses of said compounds in the treatment of diseases of uncontrolled cell growth, proliferation and/or survival, inappropriate cellular immune responses, inappropriate cellular inflammatory responses, or neurodegenerative disorders, preferably tauopathies, even more preferably, Alzheimer's disease.
Inventors:
winter-holt john james
MacIver Edward Giles
Ambler Martin
Lewis Steven
Osborne Joanne
Webb-Smith Cary
MacIver Edward Giles
Ambler Martin
Lewis Steven
Osborne Joanne
Webb-Smith Cary
Application Number:
JP2021019390A
Publication Date:
December 01, 2022
Filing Date:
February 09, 2021
Export Citation:
Assignee:
LIFEARC
International Classes:
C07D513/04; A61K31/519; A61K31/5377; A61K45/00; A61P25/28; A61P29/00; A61P35/00; A61P35/02; A61P35/04; A61P37/02; A61P43/00; C07D519/00
Domestic Patent References:
| JP2009532407A | ||||
| JP2009542749A | ||||
| JP2011504474A | ||||
| JP2012500825A | ||||
| JP2013520471A | ||||
| JP2013520472A |
Foreign References:
| WO2008057402A2 | ||||
| WO2014135480A1 | ||||
| WO2015004024A1 |
Attorney, Agent or Firm:
Hiroki Masaki
Yusaku Tokai
Horiuchi Makoto
Masako Yamauchi
Shuichi Sonomoto
Yusaku Tokai
Horiuchi Makoto
Masako Yamauchi
Shuichi Sonomoto