Title:
エピゲノム状態を制御する融合タンパク質及びその利用
Document Type and Number:
Japanese Patent JP7059965
Kind Code:
B2
Abstract:
Epigenomic states of genome DNA are altered at multiple sites to rapidly change traits by providing a fusion protein including a first region that defines a polypeptide capable of binding sequence-specifically to multiple sites on genome DNA and a second region that defines a polypeptide capable of regulating an epigenomic state.
Inventors:
Hidenori Tanaka
Akinori Ikeuchi
Risa Onoda
Hiroki Sugimoto
Nobuhiko Muramoto
Akinori Ikeuchi
Risa Onoda
Hiroki Sugimoto
Nobuhiko Muramoto
Application Number:
JP2019029415A
Publication Date:
April 26, 2022
Filing Date:
February 21, 2019
Export Citation:
Assignee:
Toyota Central R & D Labs.
International Classes:
C07K19/00; A01H1/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N15/62
Domestic Patent References:
| JP2015509957A | ||||
| JP2009532053A |
Other References:
Nat. Methods, 2016, Vol. 13, No. 2, pp. 127-137
J. Biol. Chem., 1998, Vol. 273, No. 49, pp. 33002-33010
J. Biol. Chem., 1998, Vol. 273, No. 49, pp. 33002-33010
Attorney, Agent or Firm:
Kaiyu International Patent Office