Title:
GPII▲b▼III▲a▼受容体特異性非ペプチド性インテグリン阻害剤
Document Type and Number:
Japanese Patent JP3789468
Kind Code:
B2
Abstract:
A benzazepine derivative that acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPIIbIIIa receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.
Inventors:
Blackburn, brent
Barker, peter
Gadek, Thomas
Robert McDowell
McGee, Lawrence
Somers, Todd
Web, rob
Robage, Kirk
Barker, peter
Gadek, Thomas
Robert McDowell
McGee, Lawrence
Somers, Todd
Web, rob
Robage, Kirk
Application Number:
JP50779093A
Publication Date:
June 21, 2006
Filing Date:
October 15, 1992
Export Citation:
Assignee:
Genentech, Inc.
International Classes:
C07D243/14; A61K31/55; A61K31/551; A61K31/5513; A61K31/5517; A61K31/553; A61P7/02; A61P43/00; C07D223/16; C07D243/10; C07D267/14; C07D401/06; C07D401/12
Domestic Patent References:
| JP6509074A |
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori
Kobayashi Yoshinori