Title:
オピオイド拮抗剤を含有するガレヌス組成物
Document Type and Number:
Japanese Patent JP5065548
Kind Code:
B2
Abstract:
A pharmaceutical composition for oral administration contains naloxone-, N-methylnaloxone- and/or N-methylnaltrexone-containing particles which release the active substance depending on the ambient pH. This ensures the liberation of the active substance over the whole gastrointestinal tract. The side effects caused by the use of analgesic opioids, such as constipation, are thus eliminated without reducing the analgesic effect.
Inventors:
Walter Kersten
Profilith Thomas
Profilith Thomas
Application Number:
JP52618398A
Publication Date:
November 07, 2012
Filing Date:
December 04, 1997
Export Citation:
Assignee:
Astellas Deutschland GmbH
International Classes:
A61K9/16; A61K9/20; A61K31/485; A61K9/26; A61K9/48; A61K9/50; A61K9/52; A61K9/54; A61P1/10
Domestic Patent References:
| JP8143476A | ||||
| JP5186346A | ||||
| JP383916A | ||||
| JP59500418A |
Foreign References:
| DE4325465A1 | ||||
| US4774230 |
Attorney, Agent or Firm:
Shintaro Nogawa