Title:
末端に連結された二環糖部分を有する、ギャップ化オリゴマー化合物
Document Type and Number:
Japanese Patent JP2007505138
Kind Code:
A
Abstract:
The present invention relates to bicyclic nucleosides and oligomeric compounds comprising at least one such nucleoside. These oligomeric compounds typically have enhanced binding affinity and nuclease resistance properties compared to unmodified oligomeric compounds. The oligomeric compounds are useful, for example, for investigative and therapeutic purposes.
Inventors:
Swayze, Eric Y
Migawa, michael tee
Wilshkiewitz, Tadeush Kristov
Migawa, michael tee
Wilshkiewitz, Tadeush Kristov
Application Number:
JP2006526330A
Publication Date:
March 08, 2007
Filing Date:
September 09, 2004
Export Citation:
Assignee:
Isis PharmaceuticalsInc
International Classes:
C07H21/00; A61K31/7088; A61K48/00; A61P43/00; C07H21/04; C12N15/09
Domestic Patent References:
| JP2002543214A | 2002-12-17 | |||
| JP2000297097A | 2000-10-24 | |||
| JP2002241393A | 2002-08-28 | |||
| JP2003192692A | 2003-07-09 | |||
| JPH10304889A | 1998-11-17 | |||
| JP2003524637A | 2003-08-19 | |||
| JP2002521310A | 2002-07-16 |
Foreign References:
| WO2002028875A2 | 2002-04-11 | |||
| WO2002018388A1 | 2002-03-07 |
Attorney, Agent or Firm:
Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Akiko Yamaguchi
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Akiko Yamaguchi