Title:
消化管粘膜付着性マトリックス、製剤およびコーティング剤
Document Type and Number:
Japanese Patent JP4084000
Kind Code:
B2
Abstract:
A solid matrix composition which is solid at ambient temperature, which comprises a viscogenic agent, such as an acrylic acid polymer, capable of developing viscosity on contact with water, as dispersed at least in the neighborhood of the surface layer of a matrix particle containing a polyglycerol fatty acid ester or a lipid and an active ingredient. The matrix may be such that a matrix particle containing a polyglycerol fatty acid ester or a lipid and an active ingredient has been coated with a coating composition containing at least one viscogenic agent. Such composition can adhere to the digestive tract and remain there for a prolonged period of time, thereby increasing the bioavailability of the active ingredient. Solid preparations, such as fine granules and granules, contain the above matrix composition.
More Like This:
| WO/1996/011673 | PAD FOR APPLYING MEDICAMENTS |
| JP2015110572 | CALCIUM AGENT AND PRODUCTION METHOD THEREOF |
| JP2008519036 | Nanoparticle composition of tubulin inhibitor compound |
Inventors:
Yoko Akiyama
Naoki Nagahara
Shinichiro Hirai
Naoki Nagahara
Shinichiro Hirai
Application Number:
JP2001141179A
Publication Date:
April 30, 2008
Filing Date:
May 11, 2001
Export Citation:
Assignee:
Takeda GmbH
International Classes:
A61K9/14; A61K9/16; A61K9/20; A61K9/48; A61K9/50; A61K9/58; A61K31/44; A61K45/00; A61K47/10; A61K47/12; A61K47/14; A61K47/32; A61K47/34; A61K47/38; A61K47/44; A61P1/00; A61P1/04; A61P31/04
Domestic Patent References:
| JP2001354593A | ||||
| JP63101332A | ||||
| JP62084020A | ||||
| JP62077335A | ||||
| JP2121919A | ||||
| JP2221219A | ||||
| JP2009813A | ||||
| JP61286321A | ||||
| JP55118413A | ||||
| JP2223533A | ||||
| JP2193914A | ||||
| JP57021314A |
Foreign References:
| EP0406856A1 |
Other References:
Lehr C. M. et al.,Journal of Controlled Release,1990年,Vol.13,No.1,p.51-62
Attorney, Agent or Firm:
Mitsuo Kata