Title:
ゲル組成物および方法
Document Type and Number:
Japanese Patent JP4642946
Kind Code:
B2
Abstract:
Methods and compositions for systemically or locally administering by implantation a beneficial agent to a subject are described, and include, for example, compositions having burst indices of 8 or less for systemic applications and systems releasing 10% or less of the total dose of beneficial agent in the first 24 hours after implantation for local applications. The compositions include a biocompatible polymer, a biocompatible solvent having low water miscibility that forms a viscous gel with the polymer and limits water uptake by the implant, and a beneficial agent.
Inventors:
Brodbeck, Kevin, Jay.
Gainer-Doate, Anne, Tee.
Shen, Theodore, Tee.
Gainer-Doate, Anne, Tee.
Shen, Theodore, Tee.
Application Number:
JP52902098A
Publication Date:
March 02, 2011
Filing Date:
December 18, 1997
Export Citation:
Assignee:
Alza Corporation
International Classes:
A61K9/00; A61K9/14; A61K38/00; A61K38/21; A61K38/27; A61K47/34; A61L27/00; A61K47/02; A61K47/10; A61K47/14
Domestic Patent References:
| JP8502289A | ||||
| JP8501064A | ||||
| JP4503163A | ||||
| JP2002512597A |
Foreign References:
| WO1995027481A1 |
Attorney, Agent or Firm:
Hideto Asamura
Hajime Asamura
Kajiwara Saiko
Yukihiro Ikeda
Hajime Asamura
Kajiwara Saiko
Yukihiro Ikeda