Title:
GENE EXPRESSION ENHANCER
Document Type and Number:
Japanese Patent JP2013184940
Kind Code:
A
Abstract:
To provide a new compound capable of improving a protein expression efficiency from exogenous genes.
A new compound is an SAHA (suberoylanilide hydroxamic acid) derivative modifying SAHA which is a histone deacetylase inhibitor as shown by reaction formula (A). Since the derivative has an effect of improving a gene expression efficiency, the compound is useful as a gene expression enhancer. Besides, the compound is also useful as a gene-transfer auxiliary agent used together with the exogenous gene transfer agent since the compound can effectively improve the expression of exogenous genes.
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Inventors:
NAGAOKA YASUO
AGARI SHINICHI
AGARI SHINICHI
Application Number:
JP2012052395A
Publication Date:
September 19, 2013
Filing Date:
March 09, 2012
Export Citation:
Assignee:
UNIV KANSAI
International Classes:
C07F9/113; A61K31/167; A61K31/661; A61P43/00; C07C239/14
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office
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