Title:
多発性硬化症の遺伝子発現マーカー及び治療
Document Type and Number:
Japanese Patent JP2018506275
Kind Code:
A
Abstract:
本発明は、多発性硬化症のマーカー、それらの使用、及びＩＬ−１７抗体を含むＩＬ−１７アンタゴニストでのかかるマーカーの増加したレベルを有する対象の治療に関する。【選択図】なし
Inventors:
Townsend, Michael
Setiadi, Albania Francesca
Staton, Tracy
Setiadi, Albania Francesca
Staton, Tracy
Application Number:
JP2017539266A
Publication Date:
March 08, 2018
Filing Date:
January 28, 2016
Export Citation:
Assignee:
Genentech, Incorporated
International Classes:
C12Q1/68; A61K31/136; A61K31/137; A61K31/225; A61K31/277; A61K31/573; A61K31/58; A61K38/16; A61K38/21; A61K39/395; A61K45/00; A61K45/06; A61P25/00; A61P43/00; C12N15/09; G01N33/53
Domestic Patent References:
| JP2014128279A | 2014-07-10 |
Foreign References:
| US20050266467A1 | 2005-12-01 | |||
| WO2013177101A2 | 2013-11-28 | |||
| WO2014122613A1 | 2014-08-14 | |||
| WO2008008487A2 | 2008-01-17 | |||
| US20080183395A1 | 2008-07-31 | |||
| WO2010024289A1 | 2010-03-04 | |||
| WO2010008001A1 | 2010-01-21 |
Other References:
LEE M A: "SERUM GELATINASE B, TIMP-1 AND TIMP-2 LEVELS IN MULTIPLE SCLEROSIS: A LONGITUDINAL CLINICAL 以下備考", BRAIN, vol. VOL:122, NR:2, JPN5017011496, February 1999 (1999-02-01), pages 191 - 197, XP055268757, ISSN: 0004656001, DOI: 10.1093/brain/122.2.191
RYO TOMIOKA: "BIOMARKERS FOR MULTIPLE SCLEROSIS", INTERNAL MEDICINE, vol. VOL:53, NR:5, JPN5017011498, 2014, JP, pages 361 - 365, XP055219501, ISSN: 0004656002, DOI: 10.2169/internalmedicine.53.1246
RYO TOMIOKA: "BIOMARKERS FOR MULTIPLE SCLEROSIS", INTERNAL MEDICINE, vol. VOL:53, NR:5, JPN5017011498, 2014, JP, pages 361 - 365, XP055219501, ISSN: 0004656002, DOI: 10.2169/internalmedicine.53.1246
Attorney, Agent or Firm:
Sonoda/Kobayashi Patent Business Corporation